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San Francisco is one of the top 50 tourist destinations in the world. Hosting an estimated 15 million tourists annually, tourism is the backbone of San Francisco's economy. The city is also a major financial and banking center. The financial district, Montgomery Street, is known as the "Wall Street of the West". San Francisco is home to the U.S. Federal Reserve's twelfth district and production facilities operated by the U.S. Mint. Many dot-com, IT and E-commerce headquarters are based is San Francisco. San Francisco is also a biomedical and biotechnology research center. The city was recently chosen to be the base of stem cell research in California. The city is known for its fogs, cable cars, Fisherman's Wharf, and department stores.

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