Bioinformatics, Scientist
Codexis, Inc. (Silicon Valley/Peninsula, California)

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Bioinformatics, Scientist  

Codexis is a leading developer of proprietary biocatalysts that the company believes has the potential to revolutionize chemistry-based manufacturing processes across a variety of industries.The company has used its technology platform to enable biocatalyst-based commercial-scale drug manufacturing processes and delivered biocatalysts and drug products to some of the world’s leading pharmaceutical companies. Codexis has a funded collaboration in the biofuels market, and the company is pursuing funded collaborations in several other bioindustrial markets, including carbon management, water treatment and chemicals.

We are currently seeking a scientist trained in computational modeling, structural biology, and/or enzymology to design gene libraries for cellular and metabolic engineering of biofuel producing organisms. The candidate should have a strong understanding of directed evolution and pathway engineering; a proven record designing and analyzing metabolic pathways in silico; and outstanding knowledge of microbial metabolism. 

Qualifications:

Energetic, highly self-motivated, and able to work efficiently and productively in a start-up department

 Demonstrated ability to devise creative solutions to complex biological problems  

 Able to work independently and flexibly on a variety of projects- with good multitasking and organizational skills

  Able to discover novel targets for  metabolic engineering experiments based on computational modeling and expert knowledge

 Work with analytical chemists and LIMS specialists to keep the metabolic models updated with current experimental data

 Experienced in building and analyzing metabolic models, especially genome-scale models as well as microbial genome  diversity mining

 Possessing strong statistical and analytical skills to interpret transcriptomics and metabolomics data

Skilled in the techniques of Flux balance analysis, metabolic control analysis, and the development of novel metabolic pathways

Requirements:

M.S. or Ph.D. in Bioinformatics or Computational Biology. Experience in the biotech industry is a plus, as is an understanding of LIMS systems

This position comes with a competitive compensation and benefits package, including stock options.  For more information about our plans for the future, and to be considered for this career opportunity, please visit www.codexis.com.